Urine Tests For Mycotoxins
Testing urine for mycotoxins can be helpful if you want to see if your patient has a specific mycotoxin load or to follow how severe that load is.
If the person is unable to transform/detoxify the mycotoxins, they will not show up in the urine. So, a negative result could be that the person has no mycotoxins or it could be that the person has tons of mycotoxins in their tissue and is not able to detoxify them adequately and remove them in the urine. To help them move the mycotoxins out prior to urine collection for the test, they can use far infrared saunas or other methods of sweating such as a hot tub or regular sauna for ten-30 minutes before urine collection. (Not tolerated by everyone and not to be used with a patient with POTS or adrenal insufficiency.) As an alternative they can also use liposomal glutathione or acetyl glutathione 500 mg two times per day for a week prior to the urine collection to mobilize the mycotoxins so they will show up in the urine. Either of these methods will mobilize toxins and it may make the person feel worse. If the person feels worse, this means they are mobilizing mycotoxins and they don't need to wait for a week on the glutathione, they can take the urine test immediately.
Real Time Laboratories
Real Time Laboratories (RTL) offers testing for three types of mycotoxins in the urine using ELISA technology that relies on antibodies.
They are Tricothecenes, Aflatoxins and Ochratoxin .
Tricothecenes are evaluated by using Enzyme-Linked ImmunoSorbant Assay (ELISA). The test at RTL has been validated as a qualitative test. Thus, RTL reports whether tricothecenes are PRESENT or NOT PRESENT.
Aflatoxins are evaluated using ImmunoSorbant Columns containing antibodies to the group of aflatoxins (B1, B2, G1, and G2). Results are reported as PRESENT or NOT PRESENT.
Ochratoxin A is evaluated using immunoSorbant Columns containing antibodies to the Ochratoxin A. Results are reported as PRESENT or NOT PRESENT.
Specimens that have been validated are urine, sputum, nasal washes, tissues. To discuss cost of these tests, please call the laboratory. You don't usually find mycotoxins in the blood as macrophages pick them up and remove them by storing in tissue.
Great Plains Laboratory
Great Plains Laboratory has a test called GPL-MycoTOX Profile that uses liquid chromatography mass spectrometry (LC-MS/MS) technology. They claim to be able to detect amounts in the parts per trillion for many of the mycotoxins they test. They test 8 mycotoxins that are commonly made by the molds Aspergillus, Penicillium, Stachybotrys, and Fusarium. Some of these mycotoxins may be made by other molds also, but are most commonly associated wtih these molds.
Aspergpillus: aflatoxin, ochratoxin, patulin and fumigillin - includes aflatoxin M1 which is the main metabolite of aflatoxin B1.
Stachybotrys: roridin E and verrucarin
Fusarium: zearalenone and fumonisin
has a mycotoxin test called GPL-MycoTOX Profile that includes aflatoxin M1 which is the main metabolite of aflatoxin B1.
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